Search results for "Spectroscopic [Techniques]"

showing 10 items of 30 documents

Combining HR-MAS and In Vivo MRI and MRSI Information for Robust Brain Tumor Recognition

2009

In this study we propose to classify short echotime brain MRSI data by using multimodal information coming from magnetic resonance imaging (MRI), magnetic resonance spectroscopic imaging (MRSI) and high resolution magic angle spinning (HR-MAS), and to develop an advanced pattern recognition method that could help clinicians in diagnosing brain tumors. We study the impact of using HR-MAS information in combination with in vivo information for classifying brain tumors and we investigate which parameters influence our classification results.

PhysicsNuclear magnetic resonancemedicine.diagnostic_testIn vivoPattern recognition (psychology)medicineMagic angle spinningBrain tumorHigh resolutionMagnetic resonance spectroscopic imagingMagnetic resonance imagingmedicine.disease
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High Energy, High Resolution X-Ray Spectroscopy: Microcalorimeters For Nuclear Line Astrophysics

2005

We introduce focusing optics and microcalorimeter spectroscopy to nuclear line emission astrophysics with a balloon payload concept called, B‐MINE. It is designed to probe the deepest regions of a supernova explosion by detecting 44Ti emission at 68 keV with spatial and spectral resolutions that are sufficient to determine the velocity distribution of the 44Ti emitting region. B‐MINE has a thin plastic foil telescope multilayered to maximize the reflectivity in a 20 keV band centered at 68 keV and a microcalorimeter array optimized for the same energy band. This combination provides a reduced background, an energy resolution of 50 eV and a 3σ sensitivity in 106 s of 6 × 10−8 ph cm−2 s−1 at …

PhysicsX-ray spectroscopySpectrometerPhysics::Instrumentation and Detectorsbusiness.industryAstrophysics::High Energy Astrophysical PhenomenaResolution (electron density)Astrophysicslaw.inventionTelescopeSupernovaOpticslawEmission spectrumSpectroscopybusinessX- and gamma-ray telescopes and instrumentation Photometric polarimetric and spectroscopic instrumentationLine (formation)
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Clerodane diterpenoids from Salvia splendens.

2006

Four new clerodane diterpenoids, salvisplendins A-D (1-4), have been isolated from an acetone extract of the flowers of SalVia splendens, together with an artifact (5), arising from salvisplendin D (4) by addition of diazomethane, and the already known clerodane olearin (6). The structures of the new compounds (1-5) were established mainly by 1D and 2D NMR spectroscopic studies and, in the case of salvisplendin A (1), by chemical correlation with splenolide B (7). Complete 1H and 13C NMR assignments for olearin (6), not published hitherto, are also reported.

StereochemistryPharmaceutical ScienceFlowersSalviaAnalytical ChemistryDiterpenes Clerodanechemistry.chemical_compoundFour new clerodane diterpenoids salvisplendins A-D (1-4) have been isolated from an acetone extract of the flowers of SalVia splendens together with an artifact (5) arising from salvisplendin D (4) by addition of diazomethane and the already known clerodane olearin (6). The structures of the new compounds (1-5) were established mainly by 1D and 2D NMR spectroscopic studies and in the case of salvisplendin A (1) by chemical correlation with splenolide B (7). Complete 1H and 13C NMR assignments for olearin (6) not published hitherto are also reportedDrug DiscoveryOrganic chemistrySalviaNuclear Magnetic Resonance BiomolecularPharmacologychemistry.chemical_classificationPlants MedicinalbiologyMolecular StructureChemistryDiazomethaneOrganic ChemistryCarbon-13 NMRbiology.organism_classificationChemical correlationTerpenoidComplementary and alternative medicineItalyMolecular MedicineDiterpeneTwo-dimensional nuclear magnetic resonance spectroscopyLactoneJournal of natural products
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X‐Ray Photoelectron Spectroscopy

2021

X-ray photoelectron spectroscopy (XPS) is a spectroscopic technique in the family of electron spectroscopies, that is, those methods whose probe consists of electrons instead of photons. In the case of XPS, a soft, usually monochromatic X-ray causes the emission of electrons by means of the photoelectric effect. Differences in chemical potential and/or polarizability of the molecules can cause an alteration of the binding energy; in addition to photoelectrons, an ordinary XPS spectrum may also contain Auger electrons. In an XPS system, an electron gun is used to deliver a low-energy electron flux with a low current over the illuminated spot. In an XPS instrument, an ion gun may be used with…

X-ray photoelectron spectroscopyMaterials scienceX-ray photoelectron spectroscopyPhotoelectric effectSettore CHIM/03 - Chimica Generale E InorganicaAnalytical chemistryElectron spectroscopySpectroscopic techniqueAuger electronsBinding energySpectroscopy for Materials Characterization
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Chemometric Tools to Point Out Benchmarks and Chromophores in Pigments through Spectroscopic Data Analyses

2021

Spectral preprocessing data and chemometric tools are analytical methods widely applied in several scientific contexts i.e., in archaeometric applications. A systematic classification of natural powdered pigments of organic and inorganic nature through Principal Component Analysis with a multi-instruments spectroscopic study is presented here. The methodology allows the access to elementary and molecular unique benchmarks to guide and speed up the identification of an unknown pigment and its recipe. This study is conducted on a set of 48 powdered pigments and tested on a real-case sample from the wall painting in S. Maria Delle Palate di Tusa (Messina, Italy). Four spectroscopic techniques …

ancient pigmentsspectroscopic techniquesOrganic ChemistryPharmaceutical Scienceancient pigments; spectroscopic techniques; chemometrics discrimination; elemental and molecular benchmarksArticlechemometrics discriminationAnalytical Chemistryelemental and molecular benchmarksQD241-441Chemistry (miscellaneous)Drug DiscoveryMolecular MedicinePhysical and Theoretical ChemistryMolecules; Volume 27; Issue 1; Pages: 163
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Fusingin vivoandex vivoNMR sources of information for brain tumor classification

2011

In this study we classify short echo-time brain magnetic resonance spectroscopic imaging (MRSI) data by applying a model-based canonical correlation analyses algorithm and by using, as prior knowledge, multimodal sources of information coming from high-resolution magic angle spinning (HR-MAS), MRSI and magnetic resonance imaging. The potential and limitations of fusing in vivo and ex vivo nuclear magnetic resonance sources to detect brain tumors is investigated. We present various modalities for multimodal data fusion, study the effect and the impact of using multimodal information for classifying MRSI brain glial tumors data and analyze which parameters influence the classification results…

medicine.diagnostic_testComputer sciencebusiness.industryApplied MathematicsMultimodal dataBrain tumorMagnetic resonance spectroscopic imagingMagnetic resonance imagingPattern recognitionmedicine.diseaseNuclear magnetic resonanceIn vivomedicineMagic angle spinningBrain magnetic resonance imagingArtificial intelligencebusinessInstrumentationEngineering (miscellaneous)Ex vivoMeasurement Science and Technology
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Differentiation between brain metastases and glioblastoma multiforme based on MRI, MRS and MRSI

2009

Brain metastases and glioblastoma multiforme are the most aggressive and common brain tumours in adults and they require a different clinical management. Anatomical magnetic resonance imaging (MRI) or clinical history, cannot always clearly distinguish between them. This study describes and verifies the use of magnetic resonance spectroscopy (MRS) and magnetic resonance spectroscopic imaging (MRSI) in combination with MRI for differential diagnosis of glioblastomas and metastases. Feature selection methods are applied to the magnetic resonance (MR) spectra of 121 patients and relevant features are detected. Different classification methods are used to distinguish glioblastoma multiforme and…

medicine.medical_specialtymedicine.diagnostic_testbusiness.industryMagnetic resonance spectroscopic imagingMagnetic resonance imagingmedicine.diseaseMetastasisClinical historymedicineRadiologyDifferential diagnosisMr imagesbusinessBrain metastasisGlioblastoma
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α-decay spectroscopy of the N = 130 isotones 218Ra and 220Th: Mitigation of α-particle energy summing with implanted nuclei

2019

An analysis technique has been developed in order to mitigate energy summing due to sequential short-lived α decays from nuclei implanted into a silicon detector. Using this technique, α-decay spectroscopy of the N=130 isotones 218Ra (Z=88) and 220Th (Z=90) has been performed. The energies of the α particles emitted in the 218Ra→214Rn and 220Th→216Ra ground-state-to-ground-state decays have been measured to be 8381(4) keV and 8818(13) keV, respectively. The half-lives of the ground states of 218Ra and 220Th have been measured to be 25.99(10) μs and 10.4(4) μs, respectively. The half-lives of the ground states of the α-decay daughters, 214Rn and 216Ra, have been measured to be 259(3) ns and …

nuclear data analysis and compilationalpha decayydinfysiikkaspectrometers and spectroscopic techniques
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Determination of β-decay ground state feeding of nuclei of importance for reactor applications

2020

In β-decay studies the determination of the decay probability to the ground state (g.s.) of the daughter nucleus often suffers from large systematic errors. The difficulty of the measurement is related to the absence of associated delayed γ-ray emission. In this work we revisit the 4πγ−β method proposed by Greenwood and collaborators in the 1990s, which has the potential to overcome some of the experimental difficulties. Our interest is driven by the need to determine accurately the β-intensity distributions of fission products that contribute significantly to the reactor decay heat and to the antineutrinos emitted by reactors. A number of such decays have large g.s. branches. The method is…

nuclear reactorsHigh Energy Physics::Experimentbeta decayydinfysiikkanuclear structure and decaysspectrometers and spectroscopic techniques
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Indoor pollutant identification by means of spectroscopic techniques

1995

spectroscopic techniquesIndoor pollution
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